Inhibition of PI3K by copanlisib exerts potent antitumor effects on Merkel cell carcinoma cell lines and mouse xenografts

Merkel cell carcinoma (MCC) is a highly aggressive neuroendocrine skin cancer with steadily increasing incidence and poor prognosis. Despite recent success with immunotherapy, 50% of patients still succumb to their diseases. To date, there is no Food and Drug Administration-approved targeted therapy...

Descripción completa

Detalles Bibliográficos
Autores principales: Fang, Bin, Kannan, Aarthi, Zhao, Stephanie, Nguyen, Quy H., Ejadi, Samuel, Yamamoto, Maki, Camilo Barreto, J., Zhao, Haibo, Gao, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264292/
https://www.ncbi.nlm.nih.gov/pubmed/32483262
http://dx.doi.org/10.1038/s41598-020-65637-2

Ejemplares similares

Ejemplares similares