Cargando…

Feasibility, potency, and safety of growing human mesenchymal stem cells in space for clinical application

Growing stem cells on Earth is very challenging and limited to a few population doublings. The standard two-dimensional (2D) culture environment is an unnatural condition for cell growth. Therefore, culturing stem cells aboard the International Space Station (ISS) under a microgravity environment ma...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Peng, Russell, Athena L., Lefavor, Rebecca, Durand, Nisha C., James, Elle, Harvey, Larry, Zhang, Cuiping, Countryman, Stefanie, Stodieck, Louis, Zubair, Abba C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264338/ https://www.ncbi.nlm.nih.gov/pubmed/32529028 http://dx.doi.org/10.1038/s41526-020-0106-z

Ejemplares similares

Effect of Comedications and Endotoxins on Mesenchymal Stem Cell Secretomes, Migratory and Immunomodulatory Capacity
por: Durand, Nisha, et al.
Publicado: (2019)

Insights into the use of mesenchymal stem cells in COVID-19 mediated acute respiratory failure
por: Durand, Nisha, et al.
Publicado: (2020)

Feasibility and Safety of Low-Dose Mesenchymal Stem Cell Infusion in Lung Transplant Recipients
por: Erasmus, David Brett, et al.
Publicado: (2022)

Spiders in space—orb-web-related behaviour in zero gravity
por: Zschokke, Samuel, et al.
Publicado: (2020)

Tissue Chips in Space—Challenges and Opportunities
por: Yeung, Catherine K., et al.
Publicado: (2019)

Cellular responses and gene expression profile changes due to bleomycin-induced DNA damage in human fibroblasts in space
por: Lu, Tao, et al.
Publicado: (2017)

A Molecular Genetic Basis Explaining Altered Bacterial Behavior in Space
por: Zea, Luis, et al.
Publicado: (2016)

Effects of Spaceflight on Human Induced Pluripotent Stem Cell-Derived Cardiomyocyte Structure and Function
por: Wnorowski, Alexa, et al.
Publicado: (2019)

Phenotypic Changes Exhibited by E. coli Cultured in Space
por: Zea, Luis, et al.
Publicado: (2017)

IL-10 mRNA Engineered MSCs Demonstrate Enhanced Anti-Inflammation in an Acute GvHD Model
por: Zhang, Cuiping, et al.
Publicado: (2021)

Flexible Fragment Growing Boosts Potency of Quorum‐Sensing Inhibitors against Pseudomonas aeruginosa Virulence
por: Zender, Michael, et al.
Publicado: (2019)

Feasibility, Safety, and Tolerance of Mesenchymal Stem Cell Therapy for Obstructive Chronic Lung Allograft Dysfunction
por: Keller, Cesar Ariel, et al.
Publicado: (2018)

Behavior of mice aboard the International Space Station
por: Ronca, April E., et al.
Publicado: (2019)

Prebiotic nucleic acids need space to grow
por: Whitaker, Daniel, et al.
Publicado: (2018)

High-capacity assay to quantify the clonal heterogeneity in potency of mesenchymal stem cells
por: O’Connor, Kim C, et al.
Publicado: (2011)

Preventing obesity in infants: the Growing healthy feasibility trial protocol
por: Denney-Wilson, Elizabeth, et al.
Publicado: (2015)

Challenges and translational considerations of mesenchymal stem/stromal cell therapy for Parkinson’s disease
por: Fričová, Dominika, et al.
Publicado: (2020)

Author Correction: Behavior of mice aboard the International Space Station
por: Ronca, April E., et al.
Publicado: (2019)

Potency Physically Considered
por: Millspaugh, C. F.
Publicado: (1881)

Label-free time- and space-resolved exometabolite sampling of growing plant roots through nanoporous interfaces
por: Patabadige, Damith E. W., et al.
Publicado: (2019)

Microfluidics-integrated spaceflight hardware for measuring muscle strength of Caenorhabditis elegans on the International Space Station
por: Soni, Purushottam, et al.
Publicado: (2022)

Mesenchymal stem cells for hemorrhagic stroke: status of preclinical and clinical research
por: Turnbull, Marion T., et al.
Publicado: (2019)

Skeletal muscle in MuRF1 null mice is not spared in low-gravity conditions, indicating atrophy proceeds by unique mechanisms in space
por: Cadena, Samuel M., et al.
Publicado: (2019)

Exploration Feeding and Higher Space Allocation Improve Welfare of Growing-Finishing Pigs
por: Vermeer, Herman M., et al.
Publicado: (2017)

Fluxion Potencies
por: Skinner, Thos.
Publicado: (1882)

For High Potencies
por: Fincke, B.
Publicado: (1897)

The Potency Question
Publicado: (1894)

Changes in Mouse Thymus and Spleen after Return from the STS-135 Mission in Space
por: Gridley, Daila S., et al.
Publicado: (2013)

Validation of a New Rodent Experimental System to Investigate Consequences of Long Duration Space Habitation
por: Choi, Sungshin Y., et al.
Publicado: (2020)

Osmium–arene complexes with high potency towards Mycobacterium tuberculosis
por: Coverdale, James P C, et al.
Publicado: (2021)

Potency- and Selectivity-Enhancing Mutations of Conotoxins for Nicotinic Acetylcholine Receptors Can Be Predicted Using Accurate Free-Energy Calculations
por: Katz, Dana, et al.
Publicado: (2021)

Correction: Changes in Mouse Thymus and Spleen after Return from the STS-135 Mission in Space
por: Gridley, Daila S., et al.
Publicado: (2013)

Re-rooting the learning space: minding where children's mathematics grow
por: Thom, Jennifer S
Publicado: (2012)

Rats Race to Keep Pace in the Growing Cystic Fibrosis Model Space
por: Hisert, Katherine B.
Publicado: (2020)

Variations in the Potency of Digitalis Preparations in the Tropics
por: Chopra, R. N., et al.
Publicado: (1925)

Osteogenic Potency of Nacre on Human Mesenchymal Stem Cells
por: Green, David W., et al.
Publicado: (2015)

Establishing Criteria for Human Mesenchymal Stem Cell Potency
por: Samsonraj, Rebekah M., et al.
Publicado: (2015)

Optimizing an immunomodulatory potency assay for Mesenchymal Stromal Cell
por: Hansen, Stine Bangsgaard, et al.
Publicado: (2022)

On the Potency of Insulin in the Tropics
por: Bose, Joyti Prokash
Publicado: (1924)

Antibacterial Potency of Honey
por: Albaridi, Najla A.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_87bnbq83hep6joilpmqk8qi15v