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Measuring Cancer Hallmark Mediation of the TET1 Glioma Survival Effect with Linked Neural-Network Based Mediation Experiments
This paper examines the effect of TET1 expression on survival in glioma patients using open-access data from the Genomic Data Commons. A neural network-based survival model was built on expression data from a selection of genes most affected by TET1 knockdown with a median cross-validated survival c...
Autores principales: | Luechtefeld, Thomas, Lin, Nole, Paller, Channing, Kuhns, Katherine, Laterra, John J., Bressler, Joseph P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264360/ https://www.ncbi.nlm.nih.gov/pubmed/32483272 http://dx.doi.org/10.1038/s41598-020-65369-3 |
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