Potential Preventive Strategies for Amyotrophic Lateral Sclerosis

It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as h...

Descripción completa

Detalles Bibliográficos
Autores principales: Kuraszkiewicz, B., Goszczyńska, H., Podsiadły-Marczykowska, T., Piotrkiewicz, M., Andersen, P., Gromicho, M., Grosskreutz, J., Kuźma-Kozakiewicz, M., Petri, S., Stubbendorf, B., Szacka, K., Uysal, H., de Carvalho, M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264408/
https://www.ncbi.nlm.nih.gov/pubmed/32528241
http://dx.doi.org/10.3389/fnins.2020.00428
_version_ 1783540969255206912
author Kuraszkiewicz, B.
Goszczyńska, H.
Podsiadły-Marczykowska, T.
Piotrkiewicz, M.
Andersen, P.
Gromicho, M.
Grosskreutz, J.
Kuźma-Kozakiewicz, M.
Petri, S.
Stubbendorf, B.
Szacka, K.
Uysal, H.
de Carvalho, M.
author_facet Kuraszkiewicz, B.
Goszczyńska, H.
Podsiadły-Marczykowska, T.
Piotrkiewicz, M.
Andersen, P.
Gromicho, M.
Grosskreutz, J.
Kuźma-Kozakiewicz, M.
Petri, S.
Stubbendorf, B.
Szacka, K.
Uysal, H.
de Carvalho, M.
author_sort Kuraszkiewicz, B.
collection PubMed
description It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon.
format Online
Article
Text
id pubmed-7264408
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Frontiers Media S.A.
record_format MEDLINE/PubMed
spelling pubmed-72644082020-06-10 Potential Preventive Strategies for Amyotrophic Lateral Sclerosis Kuraszkiewicz, B. Goszczyńska, H. Podsiadły-Marczykowska, T. Piotrkiewicz, M. Andersen, P. Gromicho, M. Grosskreutz, J. Kuźma-Kozakiewicz, M. Petri, S. Stubbendorf, B. Szacka, K. Uysal, H. de Carvalho, M. Front Neurosci Neuroscience It may seem useless to propose preventive measures for a disease without established pathogenesis and successful therapy, such as amyotrophic lateral sclerosis (ALS). However, we will show that ALS shares essential molecular mechanisms with aging and that established anti-aging strategies, such as healthy diet or individually adjusted exercise, may be successfully applied to ameliorate the condition of ALS patients. These strategies might be applied for prevention if persons at ALS risk could be identified early enough. Recent research advances indicate that this may happen soon. Frontiers Media S.A. 2020-05-26 /pmc/articles/PMC7264408/ /pubmed/32528241 http://dx.doi.org/10.3389/fnins.2020.00428 Text en Copyright © 2020 Kuraszkiewicz, Goszczyńska, Podsiadły-Marczykowska, Piotrkiewicz, Andersen, Gromicho, Grosskreutz, Kuźma-Kozakiewicz, Petri, Stubbendorf, Szacka, Uysal and de Carvalho. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Neuroscience
Kuraszkiewicz, B.
Goszczyńska, H.
Podsiadły-Marczykowska, T.
Piotrkiewicz, M.
Andersen, P.
Gromicho, M.
Grosskreutz, J.
Kuźma-Kozakiewicz, M.
Petri, S.
Stubbendorf, B.
Szacka, K.
Uysal, H.
de Carvalho, M.
Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_full Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_fullStr Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_full_unstemmed Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_short Potential Preventive Strategies for Amyotrophic Lateral Sclerosis
title_sort potential preventive strategies for amyotrophic lateral sclerosis
topic Neuroscience
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264408/
https://www.ncbi.nlm.nih.gov/pubmed/32528241
http://dx.doi.org/10.3389/fnins.2020.00428
work_keys_str_mv AT kuraszkiewiczb potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT goszczynskah potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT podsiadłymarczykowskat potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT piotrkiewiczm potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT andersenp potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT gromichom potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT grosskreutzj potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT kuzmakozakiewiczm potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT petris potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT stubbendorfb potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT szackak potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT uysalh potentialpreventivestrategiesforamyotrophiclateralsclerosis
AT decarvalhom potentialpreventivestrategiesforamyotrophiclateralsclerosis

Ejemplares similares