DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction
OBJECTIVE: Cellular repressor of E1A-stimulated genes (CREG), a vasculoprotective molecule, is significantly downregulated in atherosclerotic vessels through unclear mechanisms. While epigenetic regulation is involved in atherosclerosis development, it is not known if the CREG gene is epigenetically...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264464/ https://www.ncbi.nlm.nih.gov/pubmed/32067910 http://dx.doi.org/10.1016/j.redox.2020.101444 |