DNA hypermethylation: A novel mechanism of CREG gene suppression and atherosclerogenic endothelial dysfunction

OBJECTIVE: Cellular repressor of E1A-stimulated genes (CREG), a vasculoprotective molecule, is significantly downregulated in atherosclerotic vessels through unclear mechanisms. While epigenetic regulation is involved in atherosclerosis development, it is not known if the CREG gene is epigenetically...

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Detalles Bibliográficos
Autores principales: Liu, Yanxia, Tian, Xiaoxiang, Liu, Shan, Liu, Dan, Li, Yang, Liu, Meili, Zhang, Xiaolin, Yan, Chenghui, Han, Yaling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264464/
https://www.ncbi.nlm.nih.gov/pubmed/32067910
http://dx.doi.org/10.1016/j.redox.2020.101444