Ginsenoside Rh2 pretreatment and withdrawal reactivated the pentose phosphate pathway to ameliorate intracellular redox disturbance and promoted intratumoral penetration of adriamycin

Improving the limited penetration, accumulation and therapeutic effects of antitumor drugs in the avascular region of the tumor mass is crucial during chemotherapy. P-gp inhibitors have achieved little success despite significant efforts. Excessive P-gp inhibition disturbed the kinetic balance betwe...

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Detalles Bibliográficos
Autores principales: Liu, Jiali, Cai, Qingyun, Wang, Wenjie, Lu, Meng, Liu, Jianming, Zhou, Fang, Sun, Minjie, Wang, Guangji, Zhang, Jingwei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264470/
https://www.ncbi.nlm.nih.gov/pubmed/32067911
http://dx.doi.org/10.1016/j.redox.2020.101452

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