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CYP2C19 polymorphisms and outcomes of Escitalopram treatment in Brazilians with major depression
Escitalopram (ESC), a selective serotonin reuptake inhibitor indicated for the treatment of depression and anxiety disorders, is primarily metabolized by cytochrome P450 (CYP) 2C19, which is a highly polymorphic enzyme known to cause inter-individual differences in pharmacokinetics. We hypothesized...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Elsevier
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7264488/ https://www.ncbi.nlm.nih.gov/pubmed/32509985 http://dx.doi.org/10.1016/j.heliyon.2020.e04015 |