Cyclin A triggers Mitosis either via the Greatwall kinase pathway or Cyclin B

Two mitotic cyclin types, cyclin A and B, exist in higher eukaryotes, but their specialised functions in mitosis are incompletely understood. Using degron tags for rapid inducible protein removal, we analyse how acute depletion of these proteins affects mitosis. Loss of cyclin A in G2‐phase prevents...

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Detalles Bibliográficos
Autores principales: Hégarat, Nadia, Crncec, Adrijana, Suarez Peredo Rodriguez, Maria F, Echegaray Iturra, Fabio, Gu, Yan, Busby, Oliver, Lang, Paul F, Barr, Alexis R, Bakal, Chris, Kanemaki, Masato T, Lamond, Angus I, Novak, Bela, Ly, Tony, Hochegger, Helfrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265243/
https://www.ncbi.nlm.nih.gov/pubmed/32350921
http://dx.doi.org/10.15252/embj.2020104419

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