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Multistable and dynamic CRISPRi-based synthetic circuits
Gene expression control based on CRISPRi (clustered regularly interspaced short palindromic repeats interference) has emerged as a powerful tool for creating synthetic gene circuits, both in prokaryotes and in eukaryotes; yet, its lack of cooperativity has been pointed out as a potential obstacle fo...
Autores principales: | Santos-Moreno, Javier, Tasiudi, Eve, Stelling, Joerg, Schaerli, Yolanda |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265303/ https://www.ncbi.nlm.nih.gov/pubmed/32488086 http://dx.doi.org/10.1038/s41467-020-16574-1 |
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