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Chlamydomonas PKD2 organizes mastigonemes, hair-like glycoprotein polymers on cilia

Mutations in the channel protein PKD2 cause autosomal dominant polycystic kidney disease, but the function of PKD2 in cilia remains unclear. Here, we show that PKD2 targets and anchors mastigonemes, filamentous polymers of the glycoprotein MST1, to the extracellular surface of Chlamydomonas cilia. P...

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Detalles Bibliográficos
Autores principales:	Liu, Peiwei, Lou, Xiaochu, Wingfield, Jenna L., Lin, Jianfeng, Nicastro, Daniela, Lechtreck, Karl
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265326/ https://www.ncbi.nlm.nih.gov/pubmed/32348466 http://dx.doi.org/10.1083/jcb.202001122

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