Genomic analyses of early responses to radiation inglioblastoma reveal new alterations at transcription,splicing, and translation levels

High-dose radiation is the main component of glioblastoma therapy. Unfortunately, radio-resistance is a common problem and a major contributor to tumor relapse. Understanding the molecular mechanisms driving response to radiation is critical for identifying regulatory routes that could be targeted t...

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Detalles Bibliográficos
Autores principales: Choudhary, Saket, Burns, Suzanne C., Mirsafian, Hoda, Li, Wenzheng, Vo, Dat T., Qiao, Mei, Lei, Xiufen, Smith, Andrew D., Penalva, Luiz O.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265345/
https://www.ncbi.nlm.nih.gov/pubmed/32488114
http://dx.doi.org/10.1038/s41598-020-65638-1

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