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Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature

BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness an...

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Autores principales: Gopakumar, Sricharan, Steele, William J., Muir, Matthew, Bhogani, Zain, Britz, Gavin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Scientific Scholar 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265351/
https://www.ncbi.nlm.nih.gov/pubmed/33030461
http://dx.doi.org/10.25259/SNI_130_2020
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author Gopakumar, Sricharan
Steele, William J.
Muir, Matthew
Bhogani, Zain
Britz, Gavin
author_facet Gopakumar, Sricharan
Steele, William J.
Muir, Matthew
Bhogani, Zain
Britz, Gavin
author_sort Gopakumar, Sricharan
collection PubMed
description BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness and paresthesias in the lower extremities attributed to a T10-T11 intradural extramedullary mesenchymal chondrosarcoma. The patient was treated with aggressive local resection and adjuvant therapy. Here, this case and present literature are appropriately reviewed. CONCLUSION: Although uncommon, intraspinal mesenchymal chondrosarcomas warrant both radical local resection and aggressive adjuvant therapy with chemoradiation to provide the greatest chance of progression-free survival.
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spelling pubmed-72653512020-06-02 Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature Gopakumar, Sricharan Steele, William J. Muir, Matthew Bhogani, Zain Britz, Gavin Surg Neurol Int Case Report BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness and paresthesias in the lower extremities attributed to a T10-T11 intradural extramedullary mesenchymal chondrosarcoma. The patient was treated with aggressive local resection and adjuvant therapy. Here, this case and present literature are appropriately reviewed. CONCLUSION: Although uncommon, intraspinal mesenchymal chondrosarcomas warrant both radical local resection and aggressive adjuvant therapy with chemoradiation to provide the greatest chance of progression-free survival. Scientific Scholar 2020-05-02 /pmc/articles/PMC7265351/ /pubmed/33030461 http://dx.doi.org/10.25259/SNI_130_2020 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms.
spellingShingle Case Report
Gopakumar, Sricharan
Steele, William J.
Muir, Matthew
Bhogani, Zain
Britz, Gavin
Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title_full Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title_fullStr Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title_full_unstemmed Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title_short Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
title_sort intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265351/
https://www.ncbi.nlm.nih.gov/pubmed/33030461
http://dx.doi.org/10.25259/SNI_130_2020
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