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Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature
BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness an...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Scientific Scholar
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265351/ https://www.ncbi.nlm.nih.gov/pubmed/33030461 http://dx.doi.org/10.25259/SNI_130_2020 |
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author | Gopakumar, Sricharan Steele, William J. Muir, Matthew Bhogani, Zain Britz, Gavin |
author_facet | Gopakumar, Sricharan Steele, William J. Muir, Matthew Bhogani, Zain Britz, Gavin |
author_sort | Gopakumar, Sricharan |
collection | PubMed |
description | BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness and paresthesias in the lower extremities attributed to a T10-T11 intradural extramedullary mesenchymal chondrosarcoma. The patient was treated with aggressive local resection and adjuvant therapy. Here, this case and present literature are appropriately reviewed. CONCLUSION: Although uncommon, intraspinal mesenchymal chondrosarcomas warrant both radical local resection and aggressive adjuvant therapy with chemoradiation to provide the greatest chance of progression-free survival. |
format | Online Article Text |
id | pubmed-7265351 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Scientific Scholar |
record_format | MEDLINE/PubMed |
spelling | pubmed-72653512020-06-02 Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature Gopakumar, Sricharan Steele, William J. Muir, Matthew Bhogani, Zain Britz, Gavin Surg Neurol Int Case Report BACKGROUND: Mesenchymal chondrosarcoma is a rare cartilaginous neoplasm that typically involves the axial skeleton. Despite a well-circumscribed appearance, this tumor has a tendency to recur both locally and with distant metastases. CASE DESCRIPTION: A 17-year-old patient presented with numbness and paresthesias in the lower extremities attributed to a T10-T11 intradural extramedullary mesenchymal chondrosarcoma. The patient was treated with aggressive local resection and adjuvant therapy. Here, this case and present literature are appropriately reviewed. CONCLUSION: Although uncommon, intraspinal mesenchymal chondrosarcomas warrant both radical local resection and aggressive adjuvant therapy with chemoradiation to provide the greatest chance of progression-free survival. Scientific Scholar 2020-05-02 /pmc/articles/PMC7265351/ /pubmed/33030461 http://dx.doi.org/10.25259/SNI_130_2020 Text en Copyright: © 2020 Surgical Neurology International http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-Share Alike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as the author is credited and the new creations are licensed under the identical terms. |
spellingShingle | Case Report Gopakumar, Sricharan Steele, William J. Muir, Matthew Bhogani, Zain Britz, Gavin Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title | Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title_full | Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title_fullStr | Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title_full_unstemmed | Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title_short | Intraspinal mesenchymal chondrosarcoma: An argument for aggressive local resection and adjuvant therapy based on review of the literature |
title_sort | intraspinal mesenchymal chondrosarcoma: an argument for aggressive local resection and adjuvant therapy based on review of the literature |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265351/ https://www.ncbi.nlm.nih.gov/pubmed/33030461 http://dx.doi.org/10.25259/SNI_130_2020 |
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