Characterization of a new small-molecule inhibitor of HDAC6 in glioblastoma

Histone deacetylase 6 (HDAC6) is an epigenetic modifier that is an attractive pharmacological target in cancer. In this work, we show that HDAC6 is elevated in glioblastoma, the most malignant and common brain tumor in adults, in which its high levels correlate with poor patient survival and is more...

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Detalles Bibliográficos
Autores principales: Auzmendi-Iriarte, Jaione, Saenz-Antoñanzas, Ander, Mikelez-Alonso, Idoia, Carrasco-Garcia, Estefania, Tellaetxe-Abete, Maitena, Lawrie, Charles H., Sampron, Nicolás, Cortajarena, Aitziber L., Matheu, Ander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265429/
https://www.ncbi.nlm.nih.gov/pubmed/32488056
http://dx.doi.org/10.1038/s41419-020-2586-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265429/
https://www.ncbi.nlm.nih.gov/pubmed/32488056
http://dx.doi.org/10.1038/s41419-020-2586-x

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