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A unique hybrid characteristic having both pro- and anti-inflammatory phenotype transformed by repetitive low-dose lipopolysaccharide in C8-B4 microglia
Although lipopolysaccharide (LPS) is regarded as an inducer of inflammation, previous studies have suggested that repetitive low-dose LPS has neuroprotective effects via immunomodulation of microglia, resident macrophages of brain. However, microglia transformed by the stimulus of repetitive low-dos...
Autores principales: | Mizobuchi, Haruka, Yamamoto, Kazushi, Tsutsui, Shoko, Yamashita, Masafumi, Nakata, Yoko, Inagawa, Hiroyuki, Kohchi, Chie, Soma, Gen-Ichiro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265460/ https://www.ncbi.nlm.nih.gov/pubmed/32488176 http://dx.doi.org/10.1038/s41598-020-65998-8 |
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