Concurrence of multiple sclerosis and primary biliary cholangitis: Report of 3 cases

BACKGROUND: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system which damages the myelin and axon. Primary biliary cholangitis (PBC) is a slow progressive liver disease with autoimmune feature in which non-purulent destructive cholangitis and interlobular bile duct destru...

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Detalles Bibliográficos
Autores principales: Sattar, Mozhgan, Poursadeghfard, Maryam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Babol University of Medical Sciences 2020
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265518/
https://www.ncbi.nlm.nih.gov/pubmed/32509253
http://dx.doi.org/10.22088/cjim.11.2.223
Descripción
Sumario:BACKGROUND: Multiple sclerosis (MS) is an autoimmune disorder of the central nervous system which damages the myelin and axon. Primary biliary cholangitis (PBC) is a slow progressive liver disease with autoimmune feature in which non-purulent destructive cholangitis and interlobular bile duct destruction occur. Involvement of each of PBC and MS is thought to be related to environmental exposure in genetically susceptible persons. CASE PRESENTATION: Here, we aim to report 3 women 52, 27 and 51 years old with MS and PBC. CONCLUSION: Although MS seems to have an association with some autoimmune gastrointestinal disorders such as ulcerative colitis, the concurrence of MS and PBC has been rarely reported.

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