Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells

The effect of terahertz (THz) radiation on deep tissues of human body has been considered negligible due to strong absorption by water molecules. However, we observed that the energy of THz pulses transmits a millimeter thick in the aqueous solution, possibly as a shockwave, and demolishes actin fil...

Descripción completa

Detalles Bibliográficos
Autores principales: Yamazaki, Shota, Harata, Masahiko, Ueno, Yuya, Tsubouchi, Masaaki, Konagaya, Keiji, Ogawa, Yuichi, Isoyama, Goro, Otani, Chiko, Hoshina, Hiromichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265563/
https://www.ncbi.nlm.nih.gov/pubmed/32488073
http://dx.doi.org/10.1038/s41598-020-65955-5
_version_ 1783541160315191296
author Yamazaki, Shota
Harata, Masahiko
Ueno, Yuya
Tsubouchi, Masaaki
Konagaya, Keiji
Ogawa, Yuichi
Isoyama, Goro
Otani, Chiko
Hoshina, Hiromichi
author_facet Yamazaki, Shota
Harata, Masahiko
Ueno, Yuya
Tsubouchi, Masaaki
Konagaya, Keiji
Ogawa, Yuichi
Isoyama, Goro
Otani, Chiko
Hoshina, Hiromichi
author_sort Yamazaki, Shota
collection PubMed
description The effect of terahertz (THz) radiation on deep tissues of human body has been considered negligible due to strong absorption by water molecules. However, we observed that the energy of THz pulses transmits a millimeter thick in the aqueous solution, possibly as a shockwave, and demolishes actin filaments. Collapse of actin filament induced by THz irradiation was also observed in the living cells under an aqueous medium. We also confirmed that the viability of the cell was not affected under the exposure of THz pulses. The potential of THz waves as an invasive method to alter protein structure in the living cells is demonstrated.
format Online
Article
Text
id pubmed-7265563
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Nature Publishing Group UK
record_format MEDLINE/PubMed
spelling pubmed-72655632020-06-05 Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells Yamazaki, Shota Harata, Masahiko Ueno, Yuya Tsubouchi, Masaaki Konagaya, Keiji Ogawa, Yuichi Isoyama, Goro Otani, Chiko Hoshina, Hiromichi Sci Rep Article The effect of terahertz (THz) radiation on deep tissues of human body has been considered negligible due to strong absorption by water molecules. However, we observed that the energy of THz pulses transmits a millimeter thick in the aqueous solution, possibly as a shockwave, and demolishes actin filaments. Collapse of actin filament induced by THz irradiation was also observed in the living cells under an aqueous medium. We also confirmed that the viability of the cell was not affected under the exposure of THz pulses. The potential of THz waves as an invasive method to alter protein structure in the living cells is demonstrated. Nature Publishing Group UK 2020-06-02 /pmc/articles/PMC7265563/ /pubmed/32488073 http://dx.doi.org/10.1038/s41598-020-65955-5 Text en © The Author(s) 2020 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.
spellingShingle Article
Yamazaki, Shota
Harata, Masahiko
Ueno, Yuya
Tsubouchi, Masaaki
Konagaya, Keiji
Ogawa, Yuichi
Isoyama, Goro
Otani, Chiko
Hoshina, Hiromichi
Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title_full Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title_fullStr Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title_full_unstemmed Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title_short Propagation of THz irradiation energy through aqueous layers: Demolition of actin filaments in living cells
title_sort propagation of thz irradiation energy through aqueous layers: demolition of actin filaments in living cells
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265563/
https://www.ncbi.nlm.nih.gov/pubmed/32488073
http://dx.doi.org/10.1038/s41598-020-65955-5
work_keys_str_mv AT yamazakishota propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT haratamasahiko propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT uenoyuya propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT tsubouchimasaaki propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT konagayakeiji propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT ogawayuichi propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT isoyamagoro propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT otanichiko propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells
AT hoshinahiromichi propagationofthzirradiationenergythroughaqueouslayersdemolitionofactinfilamentsinlivingcells

Ejemplares similares