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Coagulation modifiers targeting SARS-CoV-2 main protease Mpro for COVID-19 treatment: an in silico approach

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection depends on viral polyprotein processing, catalysed by the main proteinase (Mpro). The solution of the SARS-CoV-2 Mpro structure allowed the investigation of potential inhibitors. This work aims to provide first evidences of the a...

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Detalles Bibliográficos
Autores principales: Biembengut, Ísis Venturi, de Souza, Tatiana de Arruda Campos Brasil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Instituto Oswaldo Cruz, Ministério da Saúde 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265679/
https://www.ncbi.nlm.nih.gov/pubmed/32490889
http://dx.doi.org/10.1590/0074-02760200179

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