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A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel

Pincer nail is a common condition characterized by excessive transverse nail curvature, progressively pinching the nail bed distally, resulting in cosmetic discomfort, pain and functional limitation. Treatment is difficult and often unsatisfactory. Surgical treatment performed by experienced physici...

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Autores principales: Vollono, Laura, Del Duca, Ester, Mazzilli, Sara, Bianchi, Luca, Cosio, Terenzio, Lanna, Caterina, Campione, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: S. Karger AG 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265718/
https://www.ncbi.nlm.nih.gov/pubmed/32518543
http://dx.doi.org/10.1159/000507915
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author Vollono, Laura
Del Duca, Ester
Mazzilli, Sara
Bianchi, Luca
Cosio, Terenzio
Lanna, Caterina
Campione, Elena
author_facet Vollono, Laura
Del Duca, Ester
Mazzilli, Sara
Bianchi, Luca
Cosio, Terenzio
Lanna, Caterina
Campione, Elena
author_sort Vollono, Laura
collection PubMed
description Pincer nail is a common condition characterized by excessive transverse nail curvature, progressively pinching the nail bed distally, resulting in cosmetic discomfort, pain and functional limitation. Treatment is difficult and often unsatisfactory. Surgical treatment performed by experienced physicians provides good outcomes. However, patients usually hesitate to undergo invasive procedures, preferring conservative treatments. Unfortunately, these mainly offer only temporary relief and recurrence rate is high. Topical tazarotene has been used in several nail conditions, but its potential remains not fully elucidated. We herewith present a case of pincer nails in a 35-year-old woman successfully treated with tazarotene 0.1% gel applied topically twice a day for 3 months who did not experience recurrence at 1-year follow-up. At 1-year follow-up, no recurrence has been observed. To our knowledge, this is the first case of pincer nails successfully treated with tazarotene 0.1% gel. With our report, we suggest topical tazarotene as a novel, effective conservative treatment of milder cases of this common, albeit disturbing condition. Although our report may not be sufficient to generalize the results, it paves the way for larger studies investigating the potential of this fast, noninvasive therapeutic agent.
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spelling pubmed-72657182020-06-08 A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel Vollono, Laura Del Duca, Ester Mazzilli, Sara Bianchi, Luca Cosio, Terenzio Lanna, Caterina Campione, Elena Case Rep Dermatol Case and Review Pincer nail is a common condition characterized by excessive transverse nail curvature, progressively pinching the nail bed distally, resulting in cosmetic discomfort, pain and functional limitation. Treatment is difficult and often unsatisfactory. Surgical treatment performed by experienced physicians provides good outcomes. However, patients usually hesitate to undergo invasive procedures, preferring conservative treatments. Unfortunately, these mainly offer only temporary relief and recurrence rate is high. Topical tazarotene has been used in several nail conditions, but its potential remains not fully elucidated. We herewith present a case of pincer nails in a 35-year-old woman successfully treated with tazarotene 0.1% gel applied topically twice a day for 3 months who did not experience recurrence at 1-year follow-up. At 1-year follow-up, no recurrence has been observed. To our knowledge, this is the first case of pincer nails successfully treated with tazarotene 0.1% gel. With our report, we suggest topical tazarotene as a novel, effective conservative treatment of milder cases of this common, albeit disturbing condition. Although our report may not be sufficient to generalize the results, it paves the way for larger studies investigating the potential of this fast, noninvasive therapeutic agent. S. Karger AG 2020-05-18 /pmc/articles/PMC7265718/ /pubmed/32518543 http://dx.doi.org/10.1159/000507915 Text en Copyright © 2020 by S. Karger AG, Basel http://creativecommons.org/licenses/by-nc/4.0/ This article is licensed under the Creative Commons Attribution-NonCommercial-4.0 International License (CC BY-NC) (http://www.karger.com/Services/OpenAccessLicense). Usage and distribution for commercial purposes requires written permission.
spellingShingle Case and Review
Vollono, Laura
Del Duca, Ester
Mazzilli, Sara
Bianchi, Luca
Cosio, Terenzio
Lanna, Caterina
Campione, Elena
A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title_full A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title_fullStr A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title_full_unstemmed A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title_short A Case of Pincer Nail Successfully Treated with Tazarotene 0.1% Gel
title_sort case of pincer nail successfully treated with tazarotene 0.1% gel
topic Case and Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265718/
https://www.ncbi.nlm.nih.gov/pubmed/32518543
http://dx.doi.org/10.1159/000507915
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