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Integrated Computational Pipeline for Single-Cell Genomic Profiling

PURPOSE: Copy-number profiling of multiple individual cells from sparse sequencing may be used to reveal a detailed picture of genomic heterogeneity and clonal organization in a tissue biopsy specimen. We sought to provide a comprehensive computational pipeline for single-cell genomics, to facilitat...

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Detalles Bibliográficos
Autores principales:	Chorbadjiev, Lubomir, Kendall, Jude, Alexander, Joan, Zhygulin, Viacheslav, Song, Junyan, Wigler, Michael, Krasnitz, Alexander
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society of Clinical Oncology 2020
Materias:	ORIGINAL REPORTS
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265781/ https://www.ncbi.nlm.nih.gov/pubmed/32432904 http://dx.doi.org/10.1200/CCI.19.00171

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