Potential role of statins in COVID-19

Patients with COVID-19 infection have an increased risk of cardiovascular complications and thrombotic events. Statins are known for their pleiotropic anti-inflammatory, antithrombotic and immunomodulatory effects. They may have a potential role as adjunctive therapy to mitigate endothelial dysfunct...

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Detalles Bibliográficos
Autores principales: Lee, Ken Cheah Hooi, Sewa, Duu Wen, Phua, Ghee Chee
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020
Materias:
Perspective
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265877/
https://www.ncbi.nlm.nih.gov/pubmed/32502659
http://dx.doi.org/10.1016/j.ijid.2020.05.115
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author Lee, Ken Cheah Hooi
Sewa, Duu Wen
Phua, Ghee Chee
author_facet Lee, Ken Cheah Hooi
Sewa, Duu Wen
Phua, Ghee Chee
author_sort Lee, Ken Cheah Hooi
collection PubMed
description Patients with COVID-19 infection have an increased risk of cardiovascular complications and thrombotic events. Statins are known for their pleiotropic anti-inflammatory, antithrombotic and immunomodulatory effects. They may have a potential role as adjunctive therapy to mitigate endothelial dysfunction and dysregulated inflammation in patients with COVID-19 infection.
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spelling pubmed-72658772020-06-02 Potential role of statins in COVID-19 Lee, Ken Cheah Hooi Sewa, Duu Wen Phua, Ghee Chee Int J Infect Dis Perspective Patients with COVID-19 infection have an increased risk of cardiovascular complications and thrombotic events. Statins are known for their pleiotropic anti-inflammatory, antithrombotic and immunomodulatory effects. They may have a potential role as adjunctive therapy to mitigate endothelial dysfunction and dysregulated inflammation in patients with COVID-19 infection. The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases. 2020-07 2020-06-02 /pmc/articles/PMC7265877/ /pubmed/32502659 http://dx.doi.org/10.1016/j.ijid.2020.05.115 Text en © 2020 The Author(s) Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Perspective
Lee, Ken Cheah Hooi
Sewa, Duu Wen
Phua, Ghee Chee
Potential role of statins in COVID-19
title Potential role of statins in COVID-19
title_full Potential role of statins in COVID-19
title_fullStr Potential role of statins in COVID-19
title_full_unstemmed Potential role of statins in COVID-19
title_short Potential role of statins in COVID-19
title_sort potential role of statins in covid-19
topic Perspective
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7265877/
https://www.ncbi.nlm.nih.gov/pubmed/32502659
http://dx.doi.org/10.1016/j.ijid.2020.05.115
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