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Inhibition of the Peroxisome Proliferator-Activated Receptor gamma Coactivator 1-alpha (PGC-1α)/Sirtuin 3 (SIRT3) Pathway Aggravates Oxidative Stress After Experimental Subarachnoid Hemorrhage

BACKGROUND: Emerging evidence shows that Sirtuin 3 (SIRT3) can exert an antioxidative effect in various neurodegenerative diseases, but whether and how SIRT3 modulates neuronal death after subarachnoid hemorrhage (SAH) remains to be elucidated. MATERIA/METHODS: Experimental SAH was induced in adult...

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Detalles Bibliográficos
Autores principales: Zhang, Ke, Cheng, Hongwei, Song, Lihua, Wei, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266085/
https://www.ncbi.nlm.nih.gov/pubmed/32447338
http://dx.doi.org/10.12659/MSM.923688

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