Cargando…

Inhibition of UBE2L6 attenuates ISGylation and impedes ATRA‐induced differentiation of leukemic cells

Ubiquitin/ISG15‐conjugating enzyme E2L6 (UBE2L6) is a critical enzyme in ISGylation, a post‐translational protein modification that conjugates the ubiquitin‐like modifier, interferon‐stimulated gene 15 (ISG15), to target substrates. Previous gene expression studies in acute promyelocytic leukemia (A...

Descripción completa

Detalles Bibliográficos
Autores principales:	Orfali, Nina, Shan‐Krauer, Deborah, O’Donovan, Tracey R., Mongan, Nigel P., Gudas, Lorraine J., Cahill, Mary R., Tschan, Mario P., McKenna, Sharon L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266268/ https://www.ncbi.nlm.nih.gov/pubmed/31820845 http://dx.doi.org/10.1002/1878-0261.12614

Ejemplares similares

All-Trans-Retinoic Acid Combined With Valproic Acid Can Promote Differentiation in Myeloid Leukemia Cells by an Autophagy Dependent Mechanism
por: Benjamin, Dalyia N., et al.
Publicado: (2022)

UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells
por: Falvey, Chloe M., et al.
Publicado: (2017)

Correction: UBE2L6/UBCH8 and ISG15 attenuate autophagy in esophageal cancer cells
por: Falvey, Chloe M., et al.
Publicado: (2020)

ISG15 and ISGylation in Human Diseases
por: Mirzalieva, Oygul, et al.
Publicado: (2022)

Targeting the Ubiquitylation and ISGylation Machinery for the Treatment of COVID-19
por: Vere, George, et al.
Publicado: (2022)

Proteomics Mapping of the ISGylation Landscape in Innate Immunity
por: Thery, Fabien, et al.
Publicado: (2021)

The Functional Roles of ISG15/ISGylation in Cancer
por: Yuan, Yin, et al.
Publicado: (2023)

Electrochemotherapy Causes Caspase-Independent Necrotic-Like Death in Pancreatic Cancer Cells
por: Fernandes, Philana, et al.
Publicado: (2019)

Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene
por: Laursen, Kristian B., et al.
Publicado: (2013)

Cuenta atrás
por: Hurwitz, Gregg Andrew
Publicado: (2004)

Hasta atrás
por: Escamilla Monroy, Ruth, et al.
Publicado: (2018)

Ubiquitin-conjugating enzyme 2C (UBE2C) is a poor prognostic biomarker in invasive breast cancer
por: Kariri, Yousif, et al.
Publicado: (2022)

Activation of RARα induces autophagy in SKBR3 breast cancer cells and depletion of key autophagy genes enhances ATRA toxicity
por: Brigger, D, et al.
Publicado: (2015)

Oncogene-mediated regulation of p53 ISGylation and functions
por: Huang, Yi-Fu, et al.
Publicado: (2014)

Upregulation of Enzymes involved in ISGylation and Ubiquitination in patients with hepatocellular carcinoma
por: Tong, Hoang Van, et al.
Publicado: (2020)

Dejados atrás : los chicos
por: Jenkins, Jerry B.
Publicado: (1999)

Atrás del viento /
por: Cerecedo, Eduardo, 1962-
Publicado: (1995)

Consecutive Inhibition of ISG15 Expression and ISGylation by Cytomegalovirus Regulators
por: Kim, Ye Ji, et al.
Publicado: (2016)

ISGylation orchestrates the degradation flux of cellular cargo toward lysosome
por: Huang, Min-Yi, et al.
Publicado: (2021)

Protein ISGylation: a posttranslational modification with implications for malignant neoplasms
por: Tecalco-Cruz, Angeles C., et al.
Publicado: (2023)

Estrogen receptor-β expression and pharmacological targeting in bladder cancer
por: KAUFFMAN, ERIC C., et al.
Publicado: (2013)

Lithium Modulates Autophagy in Esophageal and Colorectal Cancer Cells and Enhances the Efficacy of Therapeutic Agents In Vitro and In Vivo
por: O’Donovan, Tracey R., et al.
Publicado: (2015)

Decoupling deISGylating and deubiquitinating activities of the MERS virus papain-like protease
por: Clasman, Jozlyn R., et al.
Publicado: (2020)

Vesicular Stomatitis Virus G Glycoprotein and ATRA Enhanced Bystander Killing of Chemoresistant Leukemic Cells by Herpes Simplex Virus Thymidine Kinase/Ganciclovir
por: Hu, Chenxi, et al.
Publicado: (2014)

HyperISGylation of Old World Monkey ISG15 in Human Cells
por: Pattyn, Els, et al.
Publicado: (2008)

ISGylation controls exosome secretion by promoting lysosomal degradation of MVB proteins
por: Villarroya-Beltri, Carolina, et al.
Publicado: (2016)

Inflammatory osteolysis is regulated by site-specific ISGylation of the scaffold protein NEMO
por: Adapala, Naga Suresh, et al.
Publicado: (2020)

ISGylation in Innate Antiviral Immunity and Pathogen Defense Responses: A Review
por: Zhang, Mengdi, et al.
Publicado: (2021)

HERC5 and the ISGylation Pathway: Critical Modulators of the Antiviral Immune Response
por: Mathieu, Nicholas A., et al.
Publicado: (2021)

ISG15 suppresses ovulation and female fertility by ISGylating ADAMTS1
por: Chen, Yaru, et al.
Publicado: (2023)

El cuarto de atrás /
por: Martín Gaite, Carmen
Publicado: (1978)

La noche quedó atrás /
por: Valtin, Jan, 1904-1951
Publicado: (1961)

El cuarto de atrás /
por: Martín Gaite, Carmen
Publicado: (1981)

MiR-193b promotes autophagy and non-apoptotic cell death in oesophageal cancer cells
por: Nyhan, Michelle J., et al.
Publicado: (2016)

Modulation of the Host Interferon Response and ISGylation Pathway by B. pertussis Filamentous Hemagglutinin
por: Dieterich, Christine, et al.
Publicado: (2011)

ISGylation is induced in neurons by demyelination driving ISG15-dependent microglial activation
por: Clarkson, Benjamin D. S., et al.
Publicado: (2022)

ISGylation-independent protection of cell growth by USP18 following interferon stimulation
por: Clancy, Anne, et al.
Publicado: (2023)

Enforced GFI1 expression impedes human and murine leukemic cell growth
por: Hönes, Judith M., et al.
Publicado: (2017)

Deletion of the deISGylating enzyme USP18 enhances tumour cell antigenicity and radiosensitivity
por: Pinto-Fernandez, Adan, et al.
Publicado: (2020)

1979, la crisis quedó atrás?.
Publicado: (1980)

Cannot write session to /tmp/vufind_sessions/sess_7ohkinhp7nep6kfdd07gdfmn5b