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Aspirin sensitizes osimertinib‐resistant NSCLC cells in vitro and in vivo via Bim‐dependent apoptosis induction
Osimertinib, a third‐generation irreversible epidermal growth factor receptor tyrosine kinase inhibitor (EGFR‐TKI), provides marked clinical benefit for patients with EGFR‐activating mutations. Unfortunately, limited treatments exist for patients who acquire osimertinib resistance. We observed two ‘...
Autores principales: | Han, Rui, Hao, Shuai, Lu, Conghua, Zhang, Chong, Lin, Caiyu, Li, Li, Wang, Yubo, Hu, Chen, He, Yong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266273/ https://www.ncbi.nlm.nih.gov/pubmed/32239624 http://dx.doi.org/10.1002/1878-0261.12682 |
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