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A cell-based high-throughput screen identifies inhibitors that overcome P-glycoprotein (Pgp)-mediated multidrug resistance

Multidrug resistance (MDR) to chemotherapeutic drugs remains one of the major impediments to the treatment of cancer. Discovery and development of drugs that can prevent and reverse the acquisition of multidrug resistance constitute a foremost challenge in cancer therapeutics. In this work, we scree...

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Detalles Bibliográficos
Autores principales: Zahra, Rida, Furqan, Muhammad, Ullah, Rahim, Mithani, Aziz, Saleem, Rahman Shah Zaib, Faisal, Amir
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266297/
https://www.ncbi.nlm.nih.gov/pubmed/32484843
http://dx.doi.org/10.1371/journal.pone.0233993

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