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Accounting for long-range correlations in genome-wide simulations of large cohorts
Coalescent simulations are widely used to examine the effects of evolution and demographic history on the genetic makeup of populations. Thanks to recent progress in algorithms and data structures, simulators such as the widely-used msprime now provide genome-wide simulations for millions of individ...
Autores principales: | Nelson, Dominic, Kelleher, Jerome, Ragsdale, Aaron P., Moreau, Claudia, McVean, Gil, Gravel, Simon |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266353/ https://www.ncbi.nlm.nih.gov/pubmed/32369493 http://dx.doi.org/10.1371/journal.pgen.1008619 |
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