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Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases

Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of...

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Autores principales: Pala, Rajasekharreddy, Anju, V T, Dyavaiah, Madhu, Busi, Siddhardha, Nauli, Surya M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266400/
https://www.ncbi.nlm.nih.gov/pubmed/32547026
http://dx.doi.org/10.2147/IJN.S250872
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author Pala, Rajasekharreddy
Anju, V T
Dyavaiah, Madhu
Busi, Siddhardha
Nauli, Surya M
author_facet Pala, Rajasekharreddy
Anju, V T
Dyavaiah, Madhu
Busi, Siddhardha
Nauli, Surya M
author_sort Pala, Rajasekharreddy
collection PubMed
description Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs.
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spelling pubmed-72664002020-06-15 Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases Pala, Rajasekharreddy Anju, V T Dyavaiah, Madhu Busi, Siddhardha Nauli, Surya M Int J Nanomedicine Review Cardiovascular diseases (CVDs) are one of the foremost causes of high morbidity and mortality globally. Preventive, diagnostic, and treatment measures available for CVDs are not very useful, which demands promising alternative methods. Nanoscience and nanotechnology open a new window in the area of CVDs with an opportunity to achieve effective treatment, better prognosis, and less adverse effects on non-target tissues. The application of nanoparticles and nanocarriers in the area of cardiology has gathered much attention due to the properties such as passive and active targeting to the cardiac tissues, improved target specificity, and sensitivity. It has reported that more than 50% of CVDs can be treated effectively through the use of nanotechnology. The main goal of this review is to explore the recent advancements in nanoparticle-based cardiovascular drug carriers. This review also summarizes the difficulties associated with the conventional treatment modalities in comparison to the nanomedicine for CVDs. Dove 2020-05-27 /pmc/articles/PMC7266400/ /pubmed/32547026 http://dx.doi.org/10.2147/IJN.S250872 Text en © 2020 Pala et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Review
Pala, Rajasekharreddy
Anju, V T
Dyavaiah, Madhu
Busi, Siddhardha
Nauli, Surya M
Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_full Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_fullStr Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_full_unstemmed Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_short Nanoparticle-Mediated Drug Delivery for the Treatment of Cardiovascular Diseases
title_sort nanoparticle-mediated drug delivery for the treatment of cardiovascular diseases
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266400/
https://www.ncbi.nlm.nih.gov/pubmed/32547026
http://dx.doi.org/10.2147/IJN.S250872
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