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Impaired mitochondrial complex I function as a candidate driver in the biological stress response and a concomitant stress-induced brain metabolic reprogramming in male mice
Mitochondria play a critical role in bioenergetics, enabling stress adaptation, and therefore, are central in biological stress responses and stress-related complex psychopathologies. To investigate the effect of mitochondrial dysfunction on the stress response and the impact on various biological d...
Autores principales: | Emmerzaal, Tim L., Preston, Graeme, Geenen, Bram, Verweij, Vivienne, Wiesmann, Maximilian, Vasileiou, Elisavet, Grüter, Femke, de Groot, Corné, Schoorl, Jeroen, de Veer, Renske, Roelofs, Monica, Arts, Martijn, Hendriksen, Yara, Klimars, Eva, Donti, Taraka R., Graham, Brett H., Morava, Eva, Rodenburg, Richard J., Kozicz, Tamas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266820/ https://www.ncbi.nlm.nih.gov/pubmed/32488052 http://dx.doi.org/10.1038/s41398-020-0858-y |
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