Bio-Layer Interferometry Analysis of the Target Binding Activity of CRISPR-Cas Effector Complexes

CRISPR-Cas systems employ ribonucleoprotein complexes to identify nucleic acid targets with complementarity to bound CRISPR RNAs. Analyses of the high diversification of these effector complexes suggest that they can exhibit a wide spectrum of target requirements and binding affinities. Therefore, s...

Descripción completa

Detalles Bibliográficos
Autores principales: Müller-Esparza, Hanna, Osorio-Valeriano, Manuel, Steube, Niklas, Thanbichler, Martin, Randau, Lennart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266957/
https://www.ncbi.nlm.nih.gov/pubmed/32528975
http://dx.doi.org/10.3389/fmolb.2020.00098

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266957/
https://www.ncbi.nlm.nih.gov/pubmed/32528975
http://dx.doi.org/10.3389/fmolb.2020.00098

Ejemplares similares