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Bio-Layer Interferometry Analysis of the Target Binding Activity of CRISPR-Cas Effector Complexes

CRISPR-Cas systems employ ribonucleoprotein complexes to identify nucleic acid targets with complementarity to bound CRISPR RNAs. Analyses of the high diversification of these effector complexes suggest that they can exhibit a wide spectrum of target requirements and binding affinities. Therefore, s...

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Detalles Bibliográficos
Autores principales:	Müller-Esparza, Hanna, Osorio-Valeriano, Manuel, Steube, Niklas, Thanbichler, Martin, Randau, Lennart
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266957/ https://www.ncbi.nlm.nih.gov/pubmed/32528975 http://dx.doi.org/10.3389/fmolb.2020.00098

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