Cargando…

Peroxisome Proliferator-Activated Receptors: Experimental Targeting for the Treatment of Inflammatory Bowel Diseases

The peroxisome proliferator-activated receptors (PPARs) are a group of nuclear receptor proteins that promote ligand-dependent transcription of target genes that regulate energy production, lipid metabolism, and inflammation. The PPAR superfamily comprises three subtypes, PPARα, PPARγ, and PPARβ/δ,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Decara, Juan, Rivera, Patricia, López-Gambero, Antonio Jesús, Serrano, Antonia, Pavón, Francisco Javier, Baixeras, Elena, Rodríguez de Fonseca, Fernando, Suárez, Juan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2020
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7266982/ https://www.ncbi.nlm.nih.gov/pubmed/32536865 http://dx.doi.org/10.3389/fphar.2020.00730

Ejemplares similares

Acetaminophen-Induced Liver Injury Alters the Acyl Ethanolamine-Based Anti-Inflammatory Signaling System in Liver
por: Rivera, Patricia, et al.
Publicado: (2017)

The adiponectin promoter activator NP-1 induces high levels of circulating TNFα and weight loss in obese (fa/fa) Zucker rats
por: Decara, Juan, et al.
Publicado: (2018)

Environmental Enrichment, Age, and PPARα Interact to Regulate Proliferation in Neurogenic Niches
por: Pérez-Martín, Margarita, et al.
Publicado: (2016)

d‐Pinitol promotes tau dephosphorylation through a cyclin‐dependent kinase 5 regulation mechanism: A new potential approach for tauopathies?
por: Medina‐Vera, Dina, et al.
Publicado: (2022)

Chronic IL-6 Administration Desensitizes IL-6 Response in Liver, Causes Hyperleptinemia and Aggravates Steatosis in Diet-Induced-Obese Mice
por: Gavito, Ana Luisa, et al.
Publicado: (2016)

Endocrine and Metabolic Impact of Oral Ingestion of a Carob-Pod-Derived Natural-Syrup-Containing D-Pinitol: Potential Use as a Novel Sweetener in Diabetes
por: Navarro, Juan A., et al.
Publicado: (2022)

Pharmacokinetics and Endocrine Effects of an Oral Dose of D-Pinitol in Human Fasting Healthy Volunteers
por: Navarro, Juan A., et al.
Publicado: (2022)

Localization of peroxisome proliferator-activated receptor alpha (PPARα) and N-acyl phosphatidylethanolamine phospholipase D (NAPE-PLD) in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus
por: Rivera, Patricia, et al.
Publicado: (2014)

Treatment with a novel oleic-acid–dihydroxyamphetamine conjugation ameliorates non-alcoholic fatty liver disease in obese Zucker rats
por: Decara, Juan M., et al.
Publicado: (2015)

Chronic administration of recombinant IL-6 upregulates lipogenic enzyme expression and aggravates high-fat-diet-induced steatosis in IL-6-deficient mice
por: Vida, Margarita, et al.
Publicado: (2015)

Novel insights into D-Pinitol based therapies: a link between tau hyperphosphorylation and insulin resistance
por: Medina-Vera, Dina, et al.
Publicado: (2023)

D-Pinitol from Ceratonia siliqua Is an Orally Active Natural Inositol That Reduces Pancreas Insulin Secretion and Increases Circulating Ghrelin Levels in Wistar Rats
por: Navarro, Juan A., et al.
Publicado: (2020)

Pharmacological Blockade of Cannabinoid CB(1) Receptors in Diet-Induced Obesity Regulates Mitochondrial Dihydrolipoamide Dehydrogenase in Muscle
por: Arrabal, Sergio, et al.
Publicado: (2015)

Effects of Intermittent Alcohol Exposure on Emotion and Cognition: A Potential Role for the Endogenous Cannabinoid System and Neuroinflammation
por: Sanchez-Marin, Laura, et al.
Publicado: (2017)

CB(1) Blockade Potentiates Down-Regulation of Lipogenic Gene Expression in Perirenal Adipose Tissue in High Carbohydrate Diet-Induced Obesity
por: Vida, Margarita, et al.
Publicado: (2014)

Oleoylethanolamide enhances β-adrenergic-mediated thermogenesis and white-to-brown adipocyte phenotype in epididymal white adipose tissue in rat
por: Suárez, Juan, et al.
Publicado: (2014)

Computational and Biological Evaluation of N-octadecyl-N′-propylsulfamide, a Selective PPARα Agonist Structurally Related to N-acylethanolamines
por: Moreno-Santos, Inmaculada, et al.
Publicado: (2014)

Elaidyl-sulfamide, an oleoylethanolamide-modelled PPARα agonist, reduces body weight gain and plasma cholesterol in rats
por: Decara, Juan Manuel, et al.
Publicado: (2012)

The Role of Peroxisome Proliferator-Activated Receptors in Kidney Diseases
por: Gao, Jianjun, et al.
Publicado: (2022)

Pharmacological activation of CB(2) receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain
por: Rivera, Patricia, et al.
Publicado: (2015)

Pharmacological blockade of either cannabinoid CB(1) or CB(2) receptors prevents both cocaine-induced conditioned locomotion and cocaine-induced reduction of cell proliferation in the hippocampus of adult male rat
por: Blanco-Calvo, Eduardo, et al.
Publicado: (2014)

Activation of PI3K/Akt Signaling Pathway in Rat Hypothalamus Induced by an Acute Oral Administration of D-Pinitol
por: Medina-Vera, Dina, et al.
Publicado: (2021)

Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain
por: Aranda, Jesús, et al.
Publicado: (2021)

Effects of Adolescent Intermittent Alcohol Exposure on the Expression of Endocannabinoid Signaling-Related Proteins in the Spleen of Young Adult Rats
por: Pavón, Francisco Javier, et al.
Publicado: (2016)

Peroxisome proliferator-activated receptors regulate the progression and treatment of gastrointestinal cancers
por: Zhang, Min, et al.
Publicado: (2023)

Peroxisome Proliferator-Activated Receptor-Gamma Reduces ER Stress and Inflammation via Targeting NGBR Expression
por: Ma, Jialing, et al.
Publicado: (2022)

Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context
por: Rivera, Patricia, et al.
Publicado: (2015)

Salidroside Ameliorates Cardiomyocyte Hypertrophy by Upregulating Peroxisome Proliferator-Activated Receptor-α
por: Gao, Hui, et al.
Publicado: (2022)

Peroxisomal Proliferator-Activated Receptor β/δ Deficiency Induces Cognitive Alterations
por: Espinosa-Jiménez, Triana, et al.
Publicado: (2022)

Pharmacological Administration of the Isoflavone Daidzein Enhances Cell Proliferation and Reduces High Fat Diet-Induced Apoptosis and Gliosis in the Rat Hippocampus
por: Rivera, Patricia, et al.
Publicado: (2013)

Peroxisome proliferator-activated receptor gamma and its natural agonists in the treatment of kidney diseases
por: Sharma, Vinesh, et al.
Publicado: (2022)

Oleoylethanolamide Modulates BDNF-ERK Signaling and Neurogenesis in the Hippocampi of Rats Exposed to Δ(9)-THC and Ethanol Binge Drinking During Adolescence
por: Silva-Peña, Daniel, et al.
Publicado: (2019)

Evaluation of neurotrophic factors and education level as predictors of cognitive decline in alcohol use disorder
por: Requena-Ocaña, Nerea, et al.
Publicado: (2021)

The role of peroxisome proliferator-activated receptors in the tumor microenvironment, tumor cell metabolism, and anticancer therapy
por: Sun, Jiaao, et al.
Publicado: (2023)

Cocaine-Induced Behavioral Sensitization Is Associated With Changes in the Expression of Endocannabinoid and Glutamatergic Signaling Systems in the Mouse Prefrontal Cortex
por: Blanco, Eduardo, et al.
Publicado: (2014)

The Biomedical Uses of Inositols: A Nutraceutical Approach to Metabolic Dysfunction in Aging and Neurodegenerative Diseases
por: López-Gambero, Antonio J., et al.
Publicado: (2020)

Zafirlukast Is a Dual Modulator of Human Soluble Epoxide Hydrolase and Peroxisome Proliferator-Activated Receptor γ
por: Göbel, Tamara, et al.
Publicado: (2019)

SIRT6 Inhibitor, OSS_128167 Restricts Hepatitis B Virus Transcription and Replication Through Targeting Transcription Factor Peroxisome Proliferator-Activated Receptors α
por: Jiang, Hui, et al.
Publicado: (2019)

Effects of acute versus repeated cocaine exposure on the expression of endocannabinoid signaling-related proteins in the mouse cerebellum
por: Palomino, Ana, et al.
Publicado: (2014)

Localization of the cannabinoid CB1 receptor and the 2-AG synthesizing (DAGLα) and degrading (MAGL, FAAH) enzymes in cells expressing the Ca(2+)-binding proteins calbindin, calretinin, and parvalbumin in the adult rat hippocampus
por: Rivera, Patricia, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_42krcb1qolb6cbnt20d4ro08s0