Hepcidin deficiency causes bone loss through interfering with the canonical Wnt/β-catenin pathway via Forkhead box O3a

OBJECTIVE: Hepcidin deficiency is known to cause body iron accumulation and bone microarchitecture defects, but the exact underlying mechanisms of hepcidin deficiency-induced bone loss remain unclear. Our objective was to understand the molecular mechanism of hepcidin deficiency-induced bone loss. M...

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Detalles Bibliográficos
Autores principales: Li, Guangfei, Zhang, Hui, Wu, Jiadong, Wang, Aifei, Yang, Fan, Chen, Bin, Gao, Yan, Ma, Xiaowei, Xu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Chinese Speaking Orthopaedic Society 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267010/
https://www.ncbi.nlm.nih.gov/pubmed/32514392
http://dx.doi.org/10.1016/j.jot.2020.03.012

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