Lipo-Based Vaccines as an Approach to Target Dendritic Cells for Induction of T- and iNKT Cell Responses

In this study we developed a liposome-based vaccine containing palmitoylated synthetic long peptides (SLP) and alpha galactosylceramide (αGC) to specifically target dendritic cells (DC) for activation of both innate (invariant natural killer T-cells [iNKT]) and adaptive (CD8(+) T-cells) players of t...

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Detalles Bibliográficos
Autores principales: Stolk, Dorian A., de Haas, Aram, Vree, Jana, Duinkerken, Sanne, Lübbers, Joyce, van de Ven, Rieneke, Ambrosini, Martino, Kalay, Hakan, Bruijns, Sven, van der Vliet, Hans J., de Gruijl, Tanja D., van Kooyk, Yvette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267035/
https://www.ncbi.nlm.nih.gov/pubmed/32536918
http://dx.doi.org/10.3389/fimmu.2020.00990

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