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Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants

Zinc (Zn) is an essential micronutrient for plants and humans. Nearly 50% of the agriculture soils of world are Zn-deficient. The low availability of Zn reduces the yield and quality of the crops. The zinc-regulated, iron-regulated transporter-like proteins (ZIP) family and iron-regulated transporte...

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Autores principales: Ajeesh Krishna, T. P., Maharajan, T., Victor Roch, G., Ignacimuthu, Savarimuthu, Antony Ceasar, Stanislaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267038/
https://www.ncbi.nlm.nih.gov/pubmed/32536933
http://dx.doi.org/10.3389/fpls.2020.00662
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author Ajeesh Krishna, T. P.
Maharajan, T.
Victor Roch, G.
Ignacimuthu, Savarimuthu
Antony Ceasar, Stanislaus
author_facet Ajeesh Krishna, T. P.
Maharajan, T.
Victor Roch, G.
Ignacimuthu, Savarimuthu
Antony Ceasar, Stanislaus
author_sort Ajeesh Krishna, T. P.
collection PubMed
description Zinc (Zn) is an essential micronutrient for plants and humans. Nearly 50% of the agriculture soils of world are Zn-deficient. The low availability of Zn reduces the yield and quality of the crops. The zinc-regulated, iron-regulated transporter-like proteins (ZIP) family and iron-regulated transporters (IRTs) are involved in cellular uptake of Zn, its intracellular trafficking and detoxification in plants. In addition to Zn, ZIP family transporters also transport other divalent metal cations (such as Cd(2+), Fe(2+), and Cu(2+)). ZIP transporters play a crucial role in biofortification of grains with Zn. Only a very limited information is available on structural features and mechanism of Zn transport of plant ZIP family transporters. In this article, we present a detailed account on structure, function, regulations and phylogenetic relationships of plant ZIP transporters. We give an insight to structure of plant ZIPs through homology modeling and multiple sequence alignment with Bordetella bronchiseptica ZIP (BbZIP) protein whose crystal structure has been solved recently. We also provide details on ZIP transporter genes identified and characterized in rice and other plants till date. Functional characterization of plant ZIP transporters will help for the better crop yield and human health in future.
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spelling pubmed-72670382020-06-12 Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants Ajeesh Krishna, T. P. Maharajan, T. Victor Roch, G. Ignacimuthu, Savarimuthu Antony Ceasar, Stanislaus Front Plant Sci Plant Science Zinc (Zn) is an essential micronutrient for plants and humans. Nearly 50% of the agriculture soils of world are Zn-deficient. The low availability of Zn reduces the yield and quality of the crops. The zinc-regulated, iron-regulated transporter-like proteins (ZIP) family and iron-regulated transporters (IRTs) are involved in cellular uptake of Zn, its intracellular trafficking and detoxification in plants. In addition to Zn, ZIP family transporters also transport other divalent metal cations (such as Cd(2+), Fe(2+), and Cu(2+)). ZIP transporters play a crucial role in biofortification of grains with Zn. Only a very limited information is available on structural features and mechanism of Zn transport of plant ZIP family transporters. In this article, we present a detailed account on structure, function, regulations and phylogenetic relationships of plant ZIP transporters. We give an insight to structure of plant ZIPs through homology modeling and multiple sequence alignment with Bordetella bronchiseptica ZIP (BbZIP) protein whose crystal structure has been solved recently. We also provide details on ZIP transporter genes identified and characterized in rice and other plants till date. Functional characterization of plant ZIP transporters will help for the better crop yield and human health in future. Frontiers Media S.A. 2020-05-27 /pmc/articles/PMC7267038/ /pubmed/32536933 http://dx.doi.org/10.3389/fpls.2020.00662 Text en Copyright © 2020 Ajeesh Krishna, Maharajan, Victor Roch, Ignacimuthu and Antony Ceasar. http://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Plant Science
Ajeesh Krishna, T. P.
Maharajan, T.
Victor Roch, G.
Ignacimuthu, Savarimuthu
Antony Ceasar, Stanislaus
Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title_full Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title_fullStr Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title_full_unstemmed Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title_short Structure, Function, Regulation and Phylogenetic Relationship of ZIP Family Transporters of Plants
title_sort structure, function, regulation and phylogenetic relationship of zip family transporters of plants
topic Plant Science
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267038/
https://www.ncbi.nlm.nih.gov/pubmed/32536933
http://dx.doi.org/10.3389/fpls.2020.00662
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