Tyrosine Kinase Inhibitors Reduce NMDA NR1 Subunit Expression, Nuclear Translocation, and Behavioral Pain Measures in Experimental Arthritis

In the lumbar spinal cord dorsal horn, release of afferent nerve glutamate activates the neurons that relay information about injury pain. Here, we examined the effects of protein tyrosine kinase (PTK) inhibition on NMDA receptor NR1 subunit protein expression and subcellular localization in an acut...

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Detalles Bibliográficos
Autores principales: Westlund, Karin N., Lu, Ying, Zhang, Liping, Pappas, Todd C., Zhang, Wen-Ru, Taglialatela, Giulio, McIlwrath, Sabrina L., McNearney, Terry A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267073/
https://www.ncbi.nlm.nih.gov/pubmed/32536874
http://dx.doi.org/10.3389/fphys.2020.00440

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267073/
https://www.ncbi.nlm.nih.gov/pubmed/32536874
http://dx.doi.org/10.3389/fphys.2020.00440

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