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Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement
Histoplasmosis is caused by Histoplasma capsulatum. Like most fungal infections, histoplasmosis is common in immunocompromised patients. In immunocompetent patient, infection is generally asymptomatic and rarely turns into a disseminated form. Addisonian crisis as presentation of disseminated form h...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267723/ https://www.ncbi.nlm.nih.gov/pubmed/32514395 http://dx.doi.org/10.1016/j.idcr.2020.e00844 |
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author | Agrawal, Jatin Bansal, Naresh Arora, Anil |
author_facet | Agrawal, Jatin Bansal, Naresh Arora, Anil |
author_sort | Agrawal, Jatin |
collection | PubMed |
description | Histoplasmosis is caused by Histoplasma capsulatum. Like most fungal infections, histoplasmosis is common in immunocompromised patients. In immunocompetent patient, infection is generally asymptomatic and rarely turns into a disseminated form. Addisonian crisis as presentation of disseminated form has been reported in present. Here, we report a case of disseminated histoplasmosis leading to life threatening adrenal crisis and hypercalcemia in an elderly immunocompetent Indian patient. Appropriate diagnosis and anti fungal and steroid treatment lead to dramatic improvement in patient. Histoplasmosis should be considered in a immunocompetent hosts with adrenal involvement. |
format | Online Article Text |
id | pubmed-7267723 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Elsevier |
record_format | MEDLINE/PubMed |
spelling | pubmed-72677232020-06-07 Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement Agrawal, Jatin Bansal, Naresh Arora, Anil IDCases Article Histoplasmosis is caused by Histoplasma capsulatum. Like most fungal infections, histoplasmosis is common in immunocompromised patients. In immunocompetent patient, infection is generally asymptomatic and rarely turns into a disseminated form. Addisonian crisis as presentation of disseminated form has been reported in present. Here, we report a case of disseminated histoplasmosis leading to life threatening adrenal crisis and hypercalcemia in an elderly immunocompetent Indian patient. Appropriate diagnosis and anti fungal and steroid treatment lead to dramatic improvement in patient. Histoplasmosis should be considered in a immunocompetent hosts with adrenal involvement. Elsevier 2020-05-28 /pmc/articles/PMC7267723/ /pubmed/32514395 http://dx.doi.org/10.1016/j.idcr.2020.e00844 Text en © 2020 Published by Elsevier Ltd. http://creativecommons.org/licenses/by-nc-nd/4.0/ This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). |
spellingShingle | Article Agrawal, Jatin Bansal, Naresh Arora, Anil Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title | Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title_full | Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title_fullStr | Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title_full_unstemmed | Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title_short | Disseminated histoplasmosis in India presenting as addisonian crisis with epiglottis involvement |
title_sort | disseminated histoplasmosis in india presenting as addisonian crisis with epiglottis involvement |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267723/ https://www.ncbi.nlm.nih.gov/pubmed/32514395 http://dx.doi.org/10.1016/j.idcr.2020.e00844 |
work_keys_str_mv | AT agrawaljatin disseminatedhistoplasmosisinindiapresentingasaddisoniancrisiswithepiglottisinvolvement AT bansalnaresh disseminatedhistoplasmosisinindiapresentingasaddisoniancrisiswithepiglottisinvolvement AT aroraanil disseminatedhistoplasmosisinindiapresentingasaddisoniancrisiswithepiglottisinvolvement |