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MESA: automated assessment of synthetic DNA fragments and simulation of DNA synthesis, storage, sequencing and PCR errors
SUMMARY: The development of de novo DNA synthesis, polymerase chain reaction (PCR), DNA sequencing and molecular cloning gave researchers unprecedented control over DNA and DNA-mediated processes. To reduce the error probabilities of these techniques, DNA composition has to adhere to method-dependen...
Autores principales: | Schwarz, Michael, Welzel, Marius, Kabdullayeva, Tolganay, Becker, Anke, Freisleben, Bernd, Heider, Dominik |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267826/ https://www.ncbi.nlm.nih.gov/pubmed/32129840 http://dx.doi.org/10.1093/bioinformatics/btaa140 |
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