Cargando…

Neural network correlates of high‐altitude adaptive genetic variants in Tibetans: A pilot, exploratory study

Although substantial progress has been made in the identification of genetic substrates underlying physiology, neuropsychology, and brain organization, the genotype–phenotype associations remain largely unknown in the context of high‐altitude (HA) adaptation. Here, we related HA adaptive genetic var...

Descripción completa

Detalles Bibliográficos
Autores principales:	Guo, Zhiyue, Fan, Cunxiu, Li, Ting, Gesang, Luobu, Yin, Wu, Wang, Ningkai, Weng, Xuchu, Gong, Qiyong, Zhang, Jiaxing, Wang, Jinhui
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley & Sons, Inc. 2020
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267913/ https://www.ncbi.nlm.nih.gov/pubmed/32128935 http://dx.doi.org/10.1002/hbm.24954

Ejemplares similares

Reversible Brain Abnormalities in People Without Signs of Mountain Sickness During High-Altitude Exposure
por: Fan, Cunxiu, et al.
Publicado: (2016)

Whole-Genome Sequencing Identifies the Egl Nine Homologue 3 (egln3/phd3) and Protein Phosphatase 1 Regulatory Inhibitor Subunit 2 (PPP1R2P1) Associated with High-Altitude Polycythemia in Tibetans at High Altitude
por: Gesang, Luobu, et al.
Publicado: (2019)

Transcriptome reveals the overexpression of a kallikrein gene cluster (KLK1/3/7/8/12) in the Tibetans with high altitude-associated polycythemia
por: Li, Kang, et al.
Publicado: (2017)

Comparative Analysis of Gut Microbiota of Native Tibetan and Han Populations Living at Different Altitudes
por: Li, Kang, et al.
Publicado: (2016)

Cerebrovascular reactivity among native-raised high altitude residents: an fMRI study
por: Yan, Xiaodan, et al.
Publicado: (2011)

Structural Modifications of the Brain in Acclimatization to High-Altitude
por: Zhang, Jiaxing, et al.
Publicado: (2010)

Altitude-adaption of gut microbiota in Tibetan chicken
por: Du, Xiaxia, et al.
Publicado: (2022)

On the Origin of Tibetans and Their Genetic Basis in Adapting High-Altitude Environments
por: Wang, Binbin, et al.
Publicado: (2011)

Genome-Wide Transcriptional Analysis Reveals the Protection against Hypoxia-Induced Oxidative Injury in the Intestine of Tibetans via the Inhibition of GRB2/EGFR/PTPN11 Pathways
por: Li, Kang, et al.
Publicado: (2016)

Origin and adaptation to high altitude of Tibetan semi-wild wheat
por: Guo, Weilong, et al.
Publicado: (2020)

Migration and descent, adaptations to altitude and tuberculosis in Nepalis and Tibetans
por: Corbett, Stephen, et al.
Publicado: (2022)

Mitogenomic perspectives on the origin of Tibetan loaches and their adaptation to high altitude
por: Wang, Ying, et al.
Publicado: (2016)

Predictive model for estimating the risk of high-altitude pulmonary edema: a single-centre retrospective outcome-reporting study
por: Suona, Yangzong, et al.
Publicado: (2023)

GCH1 plays a role in the high-altitude adaptation of Tibetans
por: Guo, Yong-Bo, et al.
Publicado: (2017)

Key miRNAs and Genes in the High-Altitude Adaptation of Tibetan Chickens
por: Chen, Binlong, et al.
Publicado: (2022)

Genome-wide analysis reveals adaptation to high altitudes in Tibetan sheep
por: Wei, Caihong, et al.
Publicado: (2016)

Sherpas share genetic variations with Tibetans for high‐altitude adaptation
por: Bhandari, Sushil, et al.
Publicado: (2016)

Mitochondrial DNA genomes revealed different patterns of high-altitude adaptation in high-altitude Tajiks compared with Tibetans and Sherpas
por: Chen, Yu, et al.
Publicado: (2020)

Genetic signatures of high-altitude adaptation and geographic distribution in Tibetan sheep
por: Liu, Jianbin, et al.
Publicado: (2020)

Genetic adaptation of Tibetan poplar (Populus szechuanica var. tibetica) to high altitudes on the Qinghai–Tibetan Plateau
por: Zheng, Chenfei, et al.
Publicado: (2020)

Genetic Convergence in the Adaptation of Dogs and Humans to the High-Altitude Environment of the Tibetan Plateau
por: Wang, Guo-Dong, et al.
Publicado: (2014)

Population history and genomic signatures for high-altitude adaptation in Tibetan pigs
por: Ai, Huashui, et al.
Publicado: (2014)

Evidence of Polygenic Adaptation to High Altitude from Tibetan and Sherpa Genomes
por: Gnecchi-Ruscone, Guido A, et al.
Publicado: (2018)

Physiological and Biochemical Adaptations to High Altitude in Tibetan Frogs, Nanorana parkeri
por: Niu, Yonggang, et al.
Publicado: (2022)

Physiology and Proteomic Basis of Lung Adaptation to High-Altitude Hypoxia in Tibetan Sheep
por: Zhao, Pengfei, et al.
Publicado: (2022)

The Role of Introgression During the Radiation of Endemic Fishes Adapted to Living at Extreme Altitudes in the Tibetan Plateau
por: Qian, Yuting, et al.
Publicado: (2023)

EP300 contributes to high-altitude adaptation in Tibetans by regulating nitric oxide production
por: Zheng, Wang-Shan, et al.
Publicado: (2017)

Characterization of structural variation in Tibetans reveals new evidence of high-altitude adaptation and introgression
por: Quan, Cheng, et al.
Publicado: (2021)

Genomic Scan Reveals Loci under Altitude Adaptation in Tibetan and Dahe Pigs
por: Dong, Kunzhe, et al.
Publicado: (2014)

Shared and Unique Signals of High-Altitude Adaptation in Geographically Distinct Tibetan Populations
por: Wuren, Tana, et al.
Publicado: (2014)

Population Genomics Analysis Revealed Origin and High-altitude Adaptation of Tibetan Pigs
por: Ma, Yun-Fei, et al.
Publicado: (2019)

EPAS1 Gain-of-Function Mutation Contributes to High-Altitude Adaptation in Tibetan Horses
por: Liu, Xuexue, et al.
Publicado: (2019)

Large-scale genome sequencing redefines the genetic footprints of high-altitude adaptation in Tibetans
por: Zheng, Wangshan, et al.
Publicado: (2023)

De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation
por: He, Yaoxi, et al.
Publicado: (2020)

Two functional loci in the promoter of EPAS1 gene involved in high-altitude adaptation of Tibetans
por: Xu, Xiang-Hong, et al.
Publicado: (2014)

The association between altitude and serum folate levels in Tibetan adults on the Tibetan plateau
por: Yao, Shaoli, et al.
Publicado: (2022)

Physiology and Transcriptomics Analysis Reveal the Contribution of Lungs on High-Altitude Hypoxia Adaptation in Tibetan Sheep
por: Zhao, Pengfei, et al.
Publicado: (2022)

Human adaptation to the hypoxia of high altitude: the Tibetan paradigm from the pregenomic to the postgenomic era
por: Petousi, Nayia, et al.
Publicado: (2013)

Down-Regulation of EPAS1 Transcription and Genetic Adaptation of Tibetans to High-Altitude Hypoxia
por: Peng, Yi, et al.
Publicado: (2017)

Microevolutionary mechanism of high‐altitude adaptation in Tibetan chicken populations from an elevation gradient
por: Zhong, Hai‐An, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_nal26k9ena90ceq2p92pb7f6ue