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White matter hyperintensities mediate gray matter volume and processing speed relationship in cognitively unimpaired participants
White matter hyperintensities (WMH) have been extensively associated with cognitive impairment and reductions in gray matter volume (GMv) independently. This study explored whether WMH lesion volume mediates the relationship between cerebral patterns of GMv and cognition in 521 (mean age 57.7 years)...
Autores principales: | Brugulat‐Serrat, Anna, Salvadó, Gemma, Operto, Grégory, Cacciaglia, Raffaele, Sudre, Carole H., Grau‐Rivera, Oriol, Suárez‐Calvet, Marc, Falcon, Carles, Sánchez‐Benavides, Gonzalo, Gramunt, Nina, Minguillon, Carolina, Fauria, Karine, Barkhof, Frederik, Molinuevo, José L., Gispert, Juan D. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons, Inc.
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7267988/ https://www.ncbi.nlm.nih.gov/pubmed/31778002 http://dx.doi.org/10.1002/hbm.24877 |
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