Co-infusion of high-dose haploidentical donor cells and CD19-targeted CART cells achieves complete remission, successful donor engraftment and significant CART amplification in advanced ALL

Autologous CD19-targeted chimeric antigen receptor-modified T cells (CD19-CART) remarkably improved the outcome of patients with advanced B-cell acute lymphoblastic leukemia (B-ALL). However, the application and outcomes of allogeneic CART cells is still uncertain. Two patients with advanced B-ALL w...

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Detalles Bibliográficos
Autores principales: Yu, Changlin, Cai, Bo, Wang, Yao, Wu, Zhiqiang, Hu, Kaixun, Sun, Qiyun, Qiao, Jianhui, Fang, Yanhong, Zuo, Hongli, Wang, Yi, Dong, Zheng, Zhang, Zechuan, Huang, Yajing, Liu, Zhiqing, Liu, Tieqiang, Ai, Huisheng, Han, Weidong, Guo, Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268154/
https://www.ncbi.nlm.nih.gov/pubmed/32536980
http://dx.doi.org/10.1177/1758835920927605

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