First-in-human phase I trial of anti-hepatocyte growth factor antibody (YYB101) in refractory solid tumor patients

BACKGROUND: YYB101, a humanized monoclonal antibody against hepatocyte growth factor (HGF), has shown safety and efficacy in vitro and in vivo. This is a first-in-human trial of this antibody. MATERIALS AND METHODS: YYB101 was administered intravenously to refractory cancer patients once every 4 wee...

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Detalles Bibliográficos
Autores principales: Kim, Seung Tae, Hong, Jung Yong, Park, Se Hoon, Park, Joon Oh, Park, Young Whan, Park, Neunggyu, Lee, Hukeun, Hong, Sung Hee, Lee, Song-Jae, Song, Seong-Won, Kim, Kyung, Park, Young Suk, Lim, Ho Yeong, Kang, Won Ki, Nam, Do-Hyun, Lee, Jeong-Won, Park, Keunchil, Kim, Kyoung-Mee, Lee, Jeeyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2020
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268171/
https://www.ncbi.nlm.nih.gov/pubmed/32536979
http://dx.doi.org/10.1177/1758835920926796

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