SARS-CoV-2 SPIKE PROTEIN: an optimal immunological target for vaccines

COVID-19 has rapidly spread all over the world, progressing into a pandemic. This situation has urgently impelled many companies and public research institutes to concentrate their efforts on research for effective therapeutics. Here, we outline the strategies and targets currently adopted in develo...

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Detalles Bibliográficos
Autores principales: Salvatori, Giovanni, Luberto, Laura, Maffei, Mariano, Aurisicchio, Luigi, Roscilli, Giuseppe, Palombo, Fabio, Marra, Emanuele
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Commentary
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268185/
https://www.ncbi.nlm.nih.gov/pubmed/32493510
http://dx.doi.org/10.1186/s12967-020-02392-y
Descripción
Sumario:COVID-19 has rapidly spread all over the world, progressing into a pandemic. This situation has urgently impelled many companies and public research institutes to concentrate their efforts on research for effective therapeutics. Here, we outline the strategies and targets currently adopted in developing a vaccine against SARS-CoV-2. Based on previous evidence and experience with SARS and MERS, the primary focus has been the Spike protein, considered as the ideal target for COVID-19 immunotherapies.

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