Cargando…
CRISPRpred(SEQ): a sequence-based method for sgRNA on target activity prediction using traditional machine learning
BACKGROUND: The latest works on CRISPR genome editing tools mainly employs deep learning techniques. However, deep learning models lack explainability and they are harder to reproduce. We were motivated to build an accurate genome editing tool using sequence-based features and traditional machine le...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2020
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268231/ https://www.ncbi.nlm.nih.gov/pubmed/32487025 http://dx.doi.org/10.1186/s12859-020-3531-9 |