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Effect of short-term prescription opioids on DNA methylation of the OPRM1 promoter

BACKGROUND: A long-term opioid use has been associated with hypermethylation of the opioid receptor mu 1 (OPRM1) promoter. Very little is currently known about the early epigenetic response to therapeutic opioids. Here, we examine whether we can detect DNA methylation changes associated with a few d...

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Detalles Bibliográficos
Autores principales:	Sandoval-Sierra, Jose Vladimir, Salgado García, Francisco I., Brooks, Jeffrey H., Derefinko, Karen J., Mozhui, Khyobeni
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268244/ https://www.ncbi.nlm.nih.gov/pubmed/32493461 http://dx.doi.org/10.1186/s13148-020-00868-8

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