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Evaluating the efficacy and safety of GKT137831 in adults with type 1 diabetes and persistently elevated urinary albumin excretion: a statistical analysis plan

BACKGROUND: The investigational medicinal product GKT137831 is a selective inhibitor of NOX 1 and 4 isoforms of the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase family of enzymes, which has the potential to ameliorate diabetic kidney disease. An investigator-initiated, double-blind, r...

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Detalles Bibliográficos
Autores principales: De Livera, Alysha M., Reutens, Anne, Cooper, Mark, Thomas, Merlin, Jandeleit-Dahm, Karin, Shaw, Jonathan E., Salim, Agus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268311/
https://www.ncbi.nlm.nih.gov/pubmed/32493401
http://dx.doi.org/10.1186/s13063-020-04404-0