Single-cell DNA methylation sequencing reveals epigenetic alterations in mouse oocytes superovulated with different dosages of gonadotropins

BACKGROUND: Epigenetic abnormalities caused by superovulation have recently attracted increasing attention. Superovulation with exogenous hormones may prevent oocytes from establishing an appropriate epigenetic state, and this effect may extend to the methylation programming in preimplantation embry...

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Detalles Bibliográficos
Autores principales: Huo, Ying, Yan, Zhi Qiang, Yuan, Peng, Qin, Meng, Kuo, Ying, Li, Rong, Yan, Li Ying, Feng, Huai Liang, Qiao, Jie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268365/
https://www.ncbi.nlm.nih.gov/pubmed/32487258
http://dx.doi.org/10.1186/s13148-020-00866-w

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