Cargando…
Unraveling the molecular interactions involved in phase separation of glucocorticoid receptor
BACKGROUND: Functional compartmentalization has emerged as an important factor modulating the kinetics and specificity of biochemical reactions in the nucleus, including those involved in transcriptional regulation. The glucocorticoid receptor (GR) is a ligand-activated transcription factor that tra...
Autores principales: | Stortz, Martin, Pecci, Adali, Presman, Diego M., Levi, Valeria |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268505/ https://www.ncbi.nlm.nih.gov/pubmed/32487073 http://dx.doi.org/10.1186/s12915-020-00788-2 |
Ejemplares similares
-
Mapping the Dynamics of the Glucocorticoid Receptor within the Nuclear Landscape
por: Stortz, Martin, et al.
Publicado: (2017) -
The glucocorticoid receptor interferes with progesterone receptor-dependent genomic regulation in breast cancer cells
por: Ogara, Maria F, et al.
Publicado: (2019) -
Molecular dynamics simulations of the glucocorticoid receptor DNA-binding domain suggest a role of the lever-arm mobility in transcriptional output
por: Álvarez, Lautaro Damián, et al.
Publicado: (2017) -
Insights on Glucocorticoid Receptor Activity Modulation through the Binding of Rigid Steroids
por: Presman, Diego M., et al.
Publicado: (2010) -
Live Cell Imaging Unveils Multiple Domain Requirements for In Vivo Dimerization of the Glucocorticoid Receptor
por: Presman, Diego M., et al.
Publicado: (2014)