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Insulin-like growth factor receptor signaling in tumorigenesis and drug resistance: a challenge for cancer therapy

Insulin-like growth factors (IGFs) play important roles in mammalian growth, development, aging, and diseases. Aberrant IGFs signaling may lead to malignant transformation and tumor progression, thus providing the rationale for targeting IGF axis in cancer. However, clinical trials of the type I IGF...

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Detalles Bibliográficos
Autores principales:	Hua, Hui, Kong, Qingbin, Yin, Jie, Zhang, Jin, Jiang, Yangfu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268628/ https://www.ncbi.nlm.nih.gov/pubmed/32493414 http://dx.doi.org/10.1186/s13045-020-00904-3

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