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FAK activates AKT-mTOR signaling to promote the growth and progression of MMTV-Wnt1-driven basal-like mammary tumors

BACKGROUND: Breast cancer is a heterogeneous disease. Hence, stratification of patients based on the subtype of breast cancer is key to its successful treatment. Among all the breast cancer subtypes, basal-like breast cancer is the most aggressive subtype with limited treatment options. Interestingl...

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Detalles Bibliográficos
Autores principales:	Paul, Ritama, Luo, Ming, Mo, Xueying, Lu, Jason, Yeo, Syn Kok, Guan, Jun-Lin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268629/ https://www.ncbi.nlm.nih.gov/pubmed/32493400 http://dx.doi.org/10.1186/s13058-020-01298-3

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