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The lipid phosphatase Synaptojanin 1 undergoes a significant alteration in expression and solubility and is associated with brain lesions in Alzheimer’s disease

Synaptojanin 1 (SYNJ1) is a brain-enriched lipid phosphatase critically involved in autophagosomal/endosomal trafficking, synaptic vesicle recycling and metabolism of phosphoinositides. Previous studies suggest that SYNJ1 polymorphisms have significant impact on the age of onset of Alzheimer’s disea...

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Detalles Bibliográficos
Autores principales:	Ando, Kunie, Ndjim, Marième, Turbant, Sabrina, Fontaine, Gaëlle, Pregoni, Gustavo, Dauphinot, Luce, Yilmaz, Zehra, Suain, Valérie, Mansour, Salwa, Authelet, Michèle, De Dekker, Robert, Leroy, Karelle, Delatour, Benoît, Duyckaerts, Charles, Potier, Marie-Claude, Brion, Jean-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268631/ https://www.ncbi.nlm.nih.gov/pubmed/32493451 http://dx.doi.org/10.1186/s40478-020-00954-1

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