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Precursor peptide-targeted mining of more than one hundred thousand genomes expands the lanthipeptide natural product family
BACKGROUND: Lanthipeptides belong to the ribosomally synthesized and post-translationally modified peptide group of natural products and have a variety of biological activities ranging from antibiotics to antinociceptives. These peptides are cyclized through thioether crosslinks and can bear other s...
Autores principales: | Walker, Mark C., Eslami, Sara M., Hetrick, Kenton J., Ackenhusen, Sarah E., Mitchell, Douglas A., van der Donk, Wilfred A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7268733/ https://www.ncbi.nlm.nih.gov/pubmed/32493223 http://dx.doi.org/10.1186/s12864-020-06785-7 |
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